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hla (1)

  • Brian D.Tait, Caner Susal, Howard M.Gebel, Peter W.Nickerson, Andrea A.Zachary, Frans H.J.Claas, Elaine F.Reed, Robert A.Bray, Patricia Campbell, Jeremy R.Chapman, P.Toby Coates, Robert B.Colvin, Emanuele Cozzi, Ilias I.N.Doxiadis, Susan V.Fuggle, John Gill, Denis Glotz, Nils Lachmann, Thalachallour Mohanakumar, Nicole Suciu-Foca, Suchitra Sumitran-Holgersson, Kazunari Tanabe, Craig J.Taylor, Dolly B.Tyan, Angela Webster, Adriana Zeevi, and Gerhard Opelz

    Background. The introduction of solid-phase immunoassay (SPI) technology for the detection and characterization of human leukocyte antigen (HLA) antibodies in transplantation while providing greater sensitivity than was obtainable by complement-dependent lymphocytotoxicity (CDC) assays has resulted in a new paradigm with respect to the interpretation of donor-specific antibodies (DSA). Although the SPI assay performed on the Luminex instrument…

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